EID1

Across TCGA patient cohorts, EID1 mutation is significantly associated with the RNA expression of many other genes, with 3,177 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EID1-associated genes across cancer lineages are RNA5SP419, GPX5, and PPIAP25. Each is linked with EID1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EID1-to-partner and partner-to-EID1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by EID1-low versus EID1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EID1→partner) and Y-score (partner→EID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+0.646	+2.077	<.001	.001	3	2
COAD	GPX5 →	+0.159	+4.496	.001	<.001	3	1
COAD	PPIAP25 →	+0.274	+3.758	.001	.006	3	1
COAD	RPSAP38 →	+0.177	+3.769	<.001	.002	3	1
COAD	RN7SL132P →	+1.086	+3.870	<.001	.004	3	1
COAD	PCBP2P3 →	+0.137	+3.681	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,177 associations by consensus.

RNA5SP419 by EID1 expression — UCEC

Explore this box plot interactively →