EID1

Across TCGA patient cohorts, EID1 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EID1-associated genes across cancer lineages are FASN, INPP4B, and PCNA. Each is linked with EID1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EID1-to-partner and partner-to-EID1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by EID1-low versus EID1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EID1→partner) and Y-score (partner→EID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.388	+2.736	.007	<.001	3	2
UCEC	INPP4B →	-0.236	-2.700	.046	.005	3	2
UCEC	PCNA →	+0.279	+3.584	<.001	.002	3	2
UCEC	PKC-b-II_pS660 →	-0.252	-1.847	.013	.008	3	2
UCEC	C-Raf →	+0.212	+2.247	<.001	.001	3	2
UCEC	EGFR_pY1068 →	-0.317	-2.247	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

FASN by EID1 expression — UCEC

Explore this box plot interactively →