EI24P4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EI24P4 mutation is significantly associated with the RNA expression of many other genes, with 61 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EI24P4-associated genes across cancer lineages are RNU6-1284P, COX6CP3, and OR5H7P. Each is linked with EI24P4 in more than 1 cancer types. Because this analysis shows association rather than direction, both EI24P4-to-partner and partner-to-EI24P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1284P grouped by EI24P4-low versus EI24P4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EI24P4→partner) and Y-score (partner→EI24P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-1284P →+0.665+5.186.007.00732
LUADCOX6CP3 →+0.309+4.990<.001.00932
BLCAOR5H7P →+0.030+5.618.006.00231
BLCAOR8B8 →+0.027+4.899.007.00531
BLCARNU4-84P →+0.181+5.444<.001.00231
BLCACST13P →+0.071+4.605.007.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 61 associations by consensus.

RNU6-1284P by EI24P4 expression — UCEC

Box plot of RNU6-1284P in EI24P4-low vs EI24P4-high samples in UCEC.

Explore this box plot interactively →

Exploration