Across TCGA pan-cancer cohorts, EI24P1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of EI24P1’s most consistent transcriptional readouts.
The strongest signal is observed in rectum adenocarcinoma (READ), where EI24P1 RNA is repressed in tumor relative to normal tissue. In most cancer types EI24P1 is over-expressed in tumor, although a few such as READ show the opposite, repressed pattern.
READ, COAD, and LUAD are the cancer types where EI24P1 tumor–normal differential expression is most reproducible.