EI24

Across TCGA pan-cancer cohorts, EI24 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated EI24 data layer compared with 29 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher EI24 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated EI24 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, LSCC, and LUAD are the cancer types where EI24 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.751	0.525	.002	51	view →
LSCC	OS	Median	All	0.794	0.930	.003	15	view →
LUAD	OS	Median	All	0.999	0.922	.016	10	view →
PDAC	DFS	Median	IV	0.250	0.934	.024	9	view →
GBM	DFS	Quartile	All	0.459	0.252	.040	2	view →
CCRCC	OS	Tertile	III,IV	0.261	0.978	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

EI24–HNSC (DFS)

Open the HNSC breakdown →