EI24

Across TCGA patient cohorts, EI24 mutation is significantly associated with the RNA expression of many other genes, with 465 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EI24-associated genes across cancer lineages are MIR6803, GCSHP2, and CPSF7. Each is linked with EI24 in more than 1 cancer types. Because this analysis shows association rather than direction, both EI24-to-partner and partner-to-EI24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by EI24-low versus EI24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EI24→partner) and Y-score (partner→EI24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.212	+5.019	<.001	.001	3	2
BRCA	GCSHP2 →	+0.080	+5.122	.007	.008	3	2
UCEC	CPSF7 →	+0.465	+3.202	.003	.009	3	1
UCEC	CCDC3 →	-0.927	-3.584	.008	.003	3	1
UCEC	PITPNC1 →	+0.788	+3.244	.001	.008	3	1
UCEC	DDX19B →	+0.364	+2.545	.007	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 465 associations by consensus.

MIR6803 by EI24 expression — UCEC

Explore this box plot interactively →