Across TCGA patient cohorts, EHMT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,622 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EHMT2-associated proteins across cancer lineages are TRRAP, XPO1, and XPO5. Each is linked with EHMT2 in more than 6 cancer types. Because this analysis shows association rather than direction, both EHMT2-to-partner and partner-to-EHMT2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EHMT2→partner) and Y-score (partner→EHMT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TRRAP →	+0.182	+0.463	<.001	<.001	3	7
HNSC	XPO1 →	+0.253	+0.664	<.001	<.001	3	7
LSCC	XPO5 →	+0.560	+0.664	<.001	<.001	3	7
GBM	ZNF318_S709 →	+0.548	+0.533	<.001	<.001	3	7
LSCC	SMARCA5 →	+0.288	+0.578	<.001	<.001	3	7
BRCA	IPO9 →	+0.338	+0.579	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,622 associations by consensus.

Exploration

EHMT2 survival (RNA) · tumor vs normal (RNA) · all EHMT2 data types