Across TCGA cell cohorts, EHMT2 mutation is significantly associated with the RNA expression of many other genes, with 80 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EHMT2-associated genes across cancer lineages are SAXO1, ELOA3DP, and OTC. Each is linked with EHMT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EHMT2-to-partner and partner-to-EHMT2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EHMT2→partner) and Y-score (partner→EHMT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SAXO1 →	+0.042	+3.518	<.001	.008	3	2
BLOOD_Leukemia	ELOA3DP →	+0.177	+3.270	<.001	.002	3	2
BLOOD_Leukemia	OTC →	+0.101	+2.681	<.001	.008	3	2
URINARY_TRACT	TARM1 →	+0.026	+5.087	<.001	.004	3	1
SKIN	CLPS →	+0.211	+3.217	<.001	.006	3	1
SKIN	MSGN1 →	+0.038	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 80 associations by consensus.

Exploration

EHMT2 survival (RNA) · tumor vs normal (RNA) · all EHMT2 data types