EHMT1

Across TCGA patient cohorts, EHMT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,565 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EHMT1-associated proteins across cancer lineages are BRD3, FUBP3, and PHF2. Each is linked with EHMT1 in more than 6 cancer types. Because this analysis shows association rather than direction, both EHMT1-to-partner and partner-to-EHMT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EHMT1 versus BRD3 in GBM, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EHMT1→partner) and Y-score (partner→EHMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BRD3 →	+0.359	+0.427	<.001	<.001	3	7
PDAC	FUBP3 →	+0.192	+0.399	<.001	<.001	3	6
GBM	PHF2 →	+0.376	+0.398	<.001	<.001	3	5
PDAC	SMU1 →	+0.227	+0.323	.001	<.001	3	5
LSCC	SPIN1 →	+0.440	+0.517	<.001	<.001	3	5
GBM	BRD3_S263 →	+0.439	+0.349	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,565 associations by consensus.

EHMT1 vs BRD3 — GBM

Explore this scatter interactively →