EHMT1

Across TCGA cell cohorts, EHMT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,514 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EHMT1-associated GO terms across cancer lineages are Transcription pausing by RNA polymerase II, Transcription initiation-coupled chromatin remodeling, and Regulation of chromatin organization. Each is linked with EHMT1 in more than 18 cancer types. Because this analysis shows association rather than direction, both EHMT1-to-partner and partner-to-EHMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription pausing by RNA polymerase II grouped by EHMT1-low versus EHMT1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EHMT1→partner) and Y-score (partner→EHMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transcription pausing by RNA polymerase II →	+0.171	+0.770	<.001	<.001	3	19
BREAST	Transcription initiation-coupled chromatin remodeling →	+0.100	+0.901	<.001	.001	3	19
BREAST	Regulation of chromatin organization →	+0.103	+1.120	<.001	<.001	3	18
BONE	Nucleic acid transport →	+0.126	+1.091	<.001	<.001	3	18
BONE	RNA transport →	+0.126	+1.091	<.001	<.001	3	18
BONE	Negative regulation of DNA-templated transcription, elongation →	+0.107	+0.825	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,514 associations by consensus.

Transcription pausing by RNA polymerase II by EHMT1 expression — BONE

Explore this box plot interactively →