EHF

Across TCGA pan-cancer cohorts, EHF mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated EHF data layer compared with 28 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher EHF mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated EHF expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, LSCC, and PDAC are the cancer types where EHF mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	All	1.000	0.919	.010	7	view →
LSCC	OS	Quartile	All	1.000	0.610	.027	3	view →
PDAC	OS	Median	II,III,IV	0.264	0.547	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

EHF–LUAD (OS)

Open the LUAD breakdown →