EHF

Across TCGA patient cohorts, EHF mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible EHF-associated genes across cancer lineages are CD8+ T-cells, Monocytes, and CD4+ memory T-cells. Each is linked with EHF in more than 1 cancer types. Because this analysis shows association rather than direction, both EHF-to-partner and partner-to-EHF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by EHF-low versus EHF-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EHF→partner) and Y-score (partner→EHF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	CD8+ T-cells →	+0.029	+4.592	<.001	<.001	3	2
COAD	Monocytes →	+0.048	+5.734	<.001	.027	3	2
BLCA	CD4+ memory T-cells →	+0.047	+3.639	<.001	.001	3	1
BLCA	CD4+ naive T-cells →	+0.011	+3.266	.028	.027	3	1
LUAD	Osteoblast →	+0.050	+3.494	<.001	.030	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CD8+ T-cells by EHF expression — BLCA

Explore this box plot interactively →