EHF

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, EHF mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EHF-associated genes across cancer lineages are OR10W1 and SMIM9. Each is linked with EHF in more than 1 cancer types. Because this analysis shows association rather than direction, both EHF-to-partner and partner-to-EHF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by EHF-low versus EHF-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EHF→partner) and Y-score (partner→EHF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOR10W1 →+0.012+4.977.002.00731
BLOOD_LymphomaSMIM9 →+0.227+4.867<.001.00931
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR10W1 by EHF expression — LARGE_INTESTINE

Box plot of OR10W1 in EHF-low vs EHF-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration