EHF

Across TCGA cell cohorts, EHF mutation is significantly associated with the mutation status of many other genes, with 1,173 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EHF-associated genes across cancer lineages are ZNF367, THSD1, and TUBGCP4. Each is linked with EHF in more than 2 cancer types. Because this analysis shows association rather than direction, both EHF-to-partner and partner-to-EHF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF367 grouped by EHF-low versus EHF-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EHF→partner) and Y-score (partner→EHF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ZNF367 →	+4.584	+4.584	.007	.007	1	3
LARGE_INTESTINE	THSD1 →	+2.865	+4.217	.007	.007	1	2
BLOOD_Leukemia	TUBGCP4 →	+5.321	+5.894	.002	.002	1	2
LARGE_INTESTINE	PLCB2 →	+2.865	+4.217	.007	.007	1	2
LARGE_INTESTINE	SLC5A6 →	+3.672	+4.799	.002	.002	1	2
LARGE_INTESTINE	SLC3A1 →	+3.350	+4.584	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,173 associations by consensus.

ZNF367 by EHF expression — BLOOD_Lymphoma

Explore this box plot interactively →