EHD4

Across TCGA patient cohorts, EHD4 protein abundance is significantly associated with the RNA expression of many other genes, with 19,848 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EHD4-associated genes across cancer lineages are TLL1, PDGFRB, and CD93. Each is linked with EHD4 in more than 7 cancer types. Because this analysis shows association rather than direction, both EHD4-to-partner and partner-to-EHD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EHD4 versus TLL1 in CCRCC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EHD4→partner) and Y-score (partner→EHD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TLL1 →	+1.175	+0.460	<.001	<.001	3	8
OV	PDGFRB →	+0.986	+0.209	<.001	<.001	3	7
LSCC	CD93 →	+0.858	+0.397	<.001	<.001	3	7
GBM	GIMAP4 →	+0.858	+0.357	<.001	<.001	3	7
CCRCC	DIPK2B →	+0.931	+0.490	<.001	<.001	3	7
CCRCC	CLEC1A →	+0.817	+0.432	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,848 associations by consensus.

EHD4 vs TLL1 — CCRCC

Explore this scatter interactively →