EHD4

Across TCGA cell cohorts, EHD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,609 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EHD4-associated GO terms across cancer lineages are Regulation of plasminogen activation, Cellular response to environmental stimulus, and Regulation of cell-matrix adhesion. Each is linked with EHD4 in more than 12 cancer types. Because this analysis shows association rather than direction, both EHD4-to-partner and partner-to-EHD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of plasminogen activation grouped by EHD4-low versus EHD4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EHD4→partner) and Y-score (partner→EHD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of plasminogen activation →	+0.242	+2.057	.007	<.001	3	13
BONE	Cellular response to environmental stimulus →	+0.043	+1.590	<.001	<.001	3	12
BONE	Regulation of cell-matrix adhesion →	+0.165	+1.751	<.001	<.001	3	12
BONE	Regulation of proteolysis →	+0.112	+2.127	<.001	<.001	3	12
BONE	Cellular response to abiotic stimulus →	+0.043	+1.590	<.001	<.001	3	12
SOFT_TISSUE	Regulation of fibroblast proliferation →	+0.099	+1.337	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,609 associations by consensus.

Regulation of plasminogen activation by EHD4 expression — BONE

Explore this box plot interactively →