EHD4-AS1

Across TCGA pan-cancer cohorts, EHD4-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated EHD4-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher EHD4-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated EHD4-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and BLCA show a favorable association.

KIRC, MESO, and BLCA are the cancer types where EHD4-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Quartile	All	0.741	0.549	<.001	77	view →
MESO	OS	Median	II,III,IV	0.436	0.668	<.001	74	view →
BLCA	OS	Median	All	0.762	0.660	.003	54	view →
UCS	DFS	Median	All	0.165	0.390	.021	24	view →
DLBC	DFS	Median	All	0.399	0.907	.008	22	view →
BRCA	DFS	Quartile	III,IV	0.878	0.734	.015	17	view →
READ	OS	Tertile	IV	0.578	0.958	.027	17	view →
SKCM	OS	Tertile	III,IV	0.858	0.709	.003	12	view →
LAML	DFS	Tertile	All	0.458	0.720	.032	12	view →
SARC	DFS	Tertile	All	0.808	0.533	.001	12	view →
LGG	DFS	Quartile	All	0.759	0.884	.001	12	view →
THCA	DFS	Median	All	0.976	0.910	.004	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

EHD4-AS1–KIRC (OS)

Open the KIRC breakdown →