EHD3

Across TCGA patient cohorts, EHD3 protein abundance is significantly associated with the RNA expression of many other genes, with 13,890 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EHD3-associated genes across cancer lineages are DACT3, GSTM5, and ZCCHC24. Each is linked with EHD3 in more than 7 cancer types. Because this analysis shows association rather than direction, both EHD3-to-partner and partner-to-EHD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EHD3 versus DACT3 in UCEC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EHD3→partner) and Y-score (partner→EHD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DACT3 →	+0.981	+0.452	<.001	<.001	3	8
UCEC	GSTM5 →	+0.765	+0.399	<.001	<.001	3	8
BRCA	ZCCHC24 →	+1.313	+0.402	<.001	<.001	3	8
CCRCC	HECW2 →	+0.828	+0.389	<.001	<.001	3	7
GBM	DLG2 →	+0.977	+0.689	<.001	<.001	3	7
CCRCC	MFAP4 →	+1.871	+0.518	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,890 associations by consensus.

EHD3 vs DACT3 — UCEC

Explore this scatter interactively →