EHD3

Across TCGA cell cohorts, EHD3 mutation is significantly associated with the drug of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EHD3-associated genes across cancer lineages are AGI-6780, Quizartinib, and IWP-2. Each is linked with EHD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both EHD3-to-partner and partner-to-EHD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AGI-6780 grouped by EHD3-low versus EHD3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EHD3→partner) and Y-score (partner→EHD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AGI-6780 →	+0.404	+2.646	.037	.047	3	1
LARGE_INTESTINE	Quizartinib →	+0.424	+2.652	.007	.045	3	1
LARGE_INTESTINE	IWP-2 →	+0.276	+2.893	.038	.034	2	1
LARGE_INTESTINE	741909 →	+0.748	+2.649	.004	.046	2	1
LARGE_INTESTINE	Sinularin →	+0.361	+2.777	.021	.038	2	1
LARGE_INTESTINE	CZC24832 →	+0.257	+2.646	.049	.047	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

AGI-6780 by EHD3 expression — LARGE_INTESTINE

Explore this box plot interactively →