EHD1

Across TCGA pan-cancer cohorts, EHD1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated EHD1 data layer compared with 20 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher EHD1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated EHD1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, HNSC, and LUAD are the cancer types where EHD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	II,III,IV	0.887	0.283	.012	25	view →
HNSC	DFS	Quartile	III,IV	0.971	0.671	.006	12	view →
LUAD	OS	Median	III,IV	0.750	0.998	.025	9	view →
PDAC	DFS	Tertile	IV	0.203	0.752	.024	3	view →
LSCC	DFS	Median	All	0.907	0.464	.009	2	view →
GBM	OS	Median	All	0.903	0.656	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

EHD1–CCRCC (DFS)

Open the CCRCC breakdown →