EHD1

Across TCGA cell cohorts, EHD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,179 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EHD1-associated GO terms across cancer lineages are Positive regulation of myoblast fusion, Positive regulation of plasma membrane repair, and Regulation of protein K48-linked ubiquitination. Each is linked with EHD1 in more than 17 cancer types. Because this analysis shows association rather than direction, both EHD1-to-partner and partner-to-EHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of myoblast fusion grouped by EHD1-low versus EHD1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EHD1→partner) and Y-score (partner→EHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of myoblast fusion →	+0.404	+2.538	<.001	<.001	3	18
BONE	Positive regulation of plasma membrane repair →	+0.282	+1.303	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of protein K48-linked ubiquitination →	+0.164	+1.779	<.001	<.001	3	15
BONE	Regulation of cell-substrate junction organization →	+0.122	+1.103	<.001	.001	3	14
BONE	Positive regulation of syncytium formation by plasma membrane fusion →	+0.258	+1.758	<.001	<.001	3	14
CNS	Endocytic recycling →	+0.058	+1.013	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,179 associations by consensus.

Positive regulation of myoblast fusion by EHD1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →