EHD1

Across TCGA cell cohorts, EHD1 mutation is significantly associated with the RNA expression of many other genes, with 902 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EHD1-associated genes across cancer lineages are PRR23B, SSX7, and PES1. Each is linked with EHD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EHD1-to-partner and partner-to-EHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRR23B grouped by EHD1-low versus EHD1-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EHD1→partner) and Y-score (partner→EHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	PRR23B →	+0.013	+5.285	<.001	.003	3	1
STOMACH	SSX7 →	+0.433	+5.285	<.001	.003	3	1
LARGE_INTESTINE	PES1 →	+0.509	+3.675	.004	<.001	3	1
LARGE_INTESTINE	ANKRD54 →	+0.487	+2.451	.003	.009	3	1
LARGE_INTESTINE	CCDC134 →	+0.802	+3.502	<.001	.001	3	1
LARGE_INTESTINE	TTLL12 →	+0.766	+2.451	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 902 associations by consensus.

PRR23B by EHD1 expression — STOMACH

Explore this box plot interactively →