EHD1

Across TCGA cell cohorts, EHD1 mutation is significantly associated with the mutation status of many other genes, with 5,195 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EHD1-associated genes across cancer lineages are ATP2B2, TSC22D1, and NAA25. Each is linked with EHD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both EHD1-to-partner and partner-to-EHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP2B2 grouped by EHD1-low versus EHD1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EHD1→partner) and Y-score (partner→EHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	ATP2B2 →	+5.044	+5.614	.003	.003	1	5
BLOOD_Leukemia	TSC22D1 →	+3.672	+5.083	.001	.001	1	5
CNS	NAA25 →	+6.044	+6.044	.001	.001	1	4
CNS	DNMT3A →	+4.459	+5.277	.005	.005	1	4
CNS	ILF3 →	+4.459	+5.277	.005	.005	1	4
CNS	WDR33 →	+6.044	+6.044	.001	.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,195 associations by consensus.

ATP2B2 by EHD1 expression — CNS

Explore this box plot interactively →