EHBP1L1

Across TCGA pan-cancer cohorts, EHBP1L1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated EHBP1L1 data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher EHBP1L1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated EHBP1L1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PDAC show a favorable association.

HNSC, GBM, and LUAD are the cancer types where EHBP1L1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.933	0.596	.002	29	view →
GBM	OS	Median	All	0.423	0.655	.020	6	view →
LUAD	OS	Quartile	II,III,IV	0.430	0.908	.012	4	view →
CCRCC	DFS	Quartile	All	0.475	0.941	.012	4	view →
PDAC	OS	Tertile	All	0.999	0.753	.023	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

EHBP1L1–HNSC (OS)

Open the HNSC breakdown →