EHBP1L1

Across TCGA patient cohorts, EHBP1L1 mutation is significantly associated with the RNA expression of many other genes, with 2,150 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EHBP1L1-associated genes across cancer lineages are LEPROTL1, HSPA9, and RPA1. Each is linked with EHBP1L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both EHBP1L1-to-partner and partner-to-EHBP1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LEPROTL1 grouped by EHBP1L1-low versus EHBP1L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EHBP1L1→partner) and Y-score (partner→EHBP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LEPROTL1 →	+0.347	+2.914	.003	.001	3	3
UCEC	HSPA9 →	+0.438	+2.024	<.001	.005	3	3
UCEC	RPA1 →	+0.462	+1.949	.003	.008	3	3
UCEC	YARS1 →	+0.483	+2.272	<.001	.001	3	3
UCEC	TUBGCP4 →	+0.546	+3.013	<.001	<.001	3	3
UCEC	MED9 →	+0.276	+1.684	.003	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,150 associations by consensus.

LEPROTL1 by EHBP1L1 expression — UCEC

Explore this box plot interactively →