EHBP1L1

Across TCGA patient cohorts, EHBP1L1 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EHBP1L1-associated genes across cancer lineages are eEF2, p62 Lck ligand, and eIF4E. Each is linked with EHBP1L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both EHBP1L1-to-partner and partner-to-EHBP1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by EHBP1L1-low versus EHBP1L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EHBP1L1→partner) and Y-score (partner→EHBP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.367	+2.584	.003	.010	3	3
UCEC	p62 Lck ligand →	+0.378	+3.807	<.001	<.001	3	3
STAD	eIF4E →	+0.281	+3.000	<.001	.034	3	2
UCEC	A-Raf_pS299 →	-0.116	-1.584	.006	.034	3	2
UCEC	PR →	-0.220	-3.321	.012	.009	3	2
UCEC	S6_pS240_S244 →	+0.322	+1.362	.024	.037	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

eEF2 by EHBP1L1 expression — UCEC

Explore this box plot interactively →