EGR4

Across TCGA patient cohorts, EGR4 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,245 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EGR4-associated proteins across cancer lineages are RPS27L, IWS1, and S100PBP_S187. Each is linked with EGR4 in more than 2 cancer types. Because this analysis shows association rather than direction, both EGR4-to-partner and partner-to-EGR4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EGR4 versus RPS27L in GBM, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EGR4→partner) and Y-score (partner→EGR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPS27L →	-0.579	-0.444	<.001	.003	3	3
LSCC	IWS1 →	+0.272	+0.233	<.001	<.001	3	3
PDAC	S100PBP_S187 →	+0.338	+0.335	<.001	.001	3	2
LSCC	SMG5 →	+0.156	+0.157	<.001	<.001	3	2
LUAD	STAU1 →	+0.290	+0.433	<.001	<.001	3	2
UCEC	BICRAL_S934 →	-0.394	-0.387	.003	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,245 associations by consensus.

EGR4 vs RPS27L — GBM

Explore this scatter interactively →