EGR1

Across TCGA patient cohorts, EGR1 RNA expression is significantly associated with the RNA expression of many other genes, with 16,031 significant associations in total. THYM shows the largest number of these associations.

The most reproducible EGR1-associated genes across cancer lineages are FOS, EGR2, and FOSB. Each is linked with EGR1 in more than 33 cancer types. Because this analysis shows association rather than direction, both EGR1-to-partner and partner-to-EGR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EGR1 versus FOS in MESO, with a Pearson correlation of 0.92.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EGR1→partner) and Y-score (partner→EGR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
MESO	FOS →	+3.393	+3.242	<.001	<.001	3	34
PCPG	EGR2 →	+2.531	+2.727	<.001	<.001	3	33
MESO	FOSB →	+4.463	+3.111	<.001	<.001	3	33
MESO	ZFP36 →	+2.436	+3.045	<.001	<.001	3	33
CHOL	CCN1 →	+2.335	+2.504	.001	<.001	3	33
PCPG	JUNB →	+2.209	+2.752	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,031 associations by consensus.

EGR1 vs FOS — MESO

Explore this scatter interactively →