EGR1

Across TCGA patient cohorts, EGR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,359 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EGR1-associated proteins across cancer lineages are LMNB2_T34, LMNA_S423, and PRPF38B_S529. Each is linked with EGR1 in more than 7 cancer types. Because this analysis shows association rather than direction, both EGR1-to-partner and partner-to-EGR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EGR1 versus LMNB2_T34 in PDAC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EGR1→partner) and Y-score (partner→EGR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	LMNB2_T34 →	+1.053	+1.088	<.001	<.001	3	8
OV	LMNA_S423 →	+1.232	+2.172	<.001	<.001	3	7
OV	PRPF38B_S529 →	-0.945	-1.487	.001	.005	3	6
OV	TLN1_S1201 →	+1.418	+1.436	<.001	<.001	3	6
OV	UBAP1_S146 →	+0.915	+2.372	<.001	<.001	3	6
OV	ZC3H14_S390 →	+0.957	+1.760	.004	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,359 associations by consensus.

EGR1 vs LMNB2_T34 — PDAC

Explore this scatter interactively →