EGLN3

Across TCGA patient cohorts, EGLN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,179 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EGLN3-associated proteins across cancer lineages are ERO1A, LDHA, and LOXL2. Each is linked with EGLN3 in more than 7 cancer types. Because this analysis shows association rather than direction, both EGLN3-to-partner and partner-to-EGLN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EGLN3 versus ERO1A in PDAC, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EGLN3→partner) and Y-score (partner→EGLN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ERO1A →	+0.664	+1.464	<.001	<.001	3	8
PDAC	LDHA →	+0.436	+1.487	<.001	<.001	3	8
PDAC	LOXL2 →	+0.879	+1.291	<.001	<.001	3	8
PDAC	HK2 →	+0.592	+1.288	<.001	<.001	3	7
PDAC	P4HA1 →	+0.610	+1.347	<.001	<.001	3	7
PDAC	PLOD2 →	+0.728	+1.292	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,179 associations by consensus.

EGLN3 vs ERO1A — PDAC

Explore this scatter interactively →