EGLN3

Across TCGA patient cohorts, EGLN3 protein abundance is significantly associated with the RNA expression of many other genes, with 349 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EGLN3-associated genes across cancer lineages are CARD10, CENPT, and COTL1. Each is linked with EGLN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both EGLN3-to-partner and partner-to-EGLN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EGLN3 versus CARD10 in LSCC, with a Pearson correlation of -0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EGLN3→partner) and Y-score (partner→EGLN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CARD10 →	-1.107	-0.368	.004	.008	3	1
LSCC	CENPT →	-0.657	-0.553	.006	.005	3	1
LSCC	COTL1 →	-1.100	-0.368	.002	.008	3	1
LSCC	CLASRP →	-0.547	-0.367	<.001	.008	3	1
LSCC	PPP6R1 →	-0.788	-0.368	.003	.008	3	1
LSCC	LILRB5 →	-1.362	-0.436	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 349 associations by consensus.

EGLN3 vs CARD10 — LSCC

Explore this scatter interactively →