EGLN3

Across TCGA cell cohorts, EGLN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,463 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible EGLN3-associated GO terms across cancer lineages are Response to nutrient, Glucose catabolic process, and Endosome organization. Each is linked with EGLN3 in more than 8 cancer types. Because this analysis shows association rather than direction, both EGLN3-to-partner and partner-to-EGLN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to nutrient grouped by EGLN3-low versus EGLN3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EGLN3→partner) and Y-score (partner→EGLN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Response to nutrient →	+0.064	+1.855	<.001	.002	3	9
CNS	Glucose catabolic process →	+0.074	+1.726	.001	<.001	3	7
OVARY	Endosome organization →	+0.046	+2.872	.001	<.001	3	7
OESOPHAGUS	SRP-dependent cotranslational protein targeting to membrane, translocation →	+0.131	+2.385	.006	.003	3	7
BLOOD_Lymphoma	Process utilizing autophagic mechanism →	+0.023	+0.931	.001	.007	3	7
BLOOD_Lymphoma	Autophagy →	+0.023	+0.931	.001	.007	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,463 associations by consensus.

Response to nutrient by EGLN3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →