EGLN3-AS1

Across TCGA pan-cancer cohorts, EGLN3-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated EGLN3-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher EGLN3-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EGLN3-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and UVM show a favorable association.

KICH, KIRC, and LIHC are the cancer types where EGLN3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	All	0.410	0.893	<.001	105	view →
KIRC	OS	Tertile	All	0.751	0.583	<.001	89	view →
LIHC	OS	Tertile	All	0.344	0.560	<.001	86	view →
ACC	DFS	Tertile	All	0.048	0.667	<.001	54	view →
THCA	OS	Tertile	IV	0.095	0.966	<.001	39	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	36	view →
UVM	DFS	Tertile	II,III,IV	0.793	0.441	.011	18	view →
UCEC	DFS	Tertile	All	0.737	0.848	.023	18	view →
PAAD	OS	Median	III,IV	0.629	1.000	.022	13	view →
SKCM	DFS	Tertile	IV	0.045	0.471	.016	9	view →
ESCA	DFS	Tertile	All	0.429	0.577	.026	9	view →
PCPG	DFS	Tertile	All	0.535	0.936	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

EGLN3-AS1–KICH (OS)

Open the KICH breakdown →