EGLN2

Across TCGA patient cohorts, EGLN2 mutation is significantly associated with the RNA expression of many other genes, with 3,672 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EGLN2-associated genes across cancer lineages are LINC01072, MIR4311, and RN7SL135P. Each is linked with EGLN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both EGLN2-to-partner and partner-to-EGLN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01072 grouped by EGLN2-low versus EGLN2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EGLN2→partner) and Y-score (partner→EGLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01072 →	+0.078	+1.836	.008	.005	3	3
CESC	MIR4311 →	+0.247	+4.559	.004	.006	3	2
COAD	RN7SL135P →	+0.266	+4.962	.004	.003	3	2
COAD	RN7SL25P →	+0.193	+4.484	.005	.002	3	2
HNSC	OR4F15 →	+0.063	+5.303	<.001	.006	3	2
HNSC	RNU1-101P →	+0.305	+6.763	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,672 associations by consensus.

LINC01072 by EGLN2 expression — UCEC

Explore this box plot interactively →