EGFR-AS1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EGFR-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,359 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EGFR-AS1-associated proteins across cancer lineages are EGFR, EGFR_S1064, and EGFR_T693. Each is linked with EGFR-AS1 in more than 8 cancer types. Because this analysis shows association rather than direction, both EGFR-AS1-to-partner and partner-to-EGFR-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EGFR-AS1→partner) and Y-score (partner→EGFR-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMEGFR →+2.116+4.012<.001<.00139
GBMEGFR_S1064 →+1.796+3.244<.001<.00136
GBMEGFR_T693 →+1.046+3.066<.001<.00136
GBMLANCL2 →+0.972+1.772<.001<.00135
LSCCEGFR_S1166 →+2.231+2.218.001<.00135
GBMPHLDA1 →+1.176+3.606<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,359 associations by consensus.

Exploration