EGFLAM

Across TCGA pan-cancer cohorts, EGFLAM mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated EGFLAM data layer compared with 24 for mass-spec protein and 11 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher EGFLAM mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated EGFLAM expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

UCEC, HNSC, and LUAD are the cancer types where EGFLAM mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	0.363	1.000	.005	12	view →
HNSC	DFS	Quartile	III,IV	1.000	0.861	.015	4	view →
LUAD	DFS	Quartile	II,III,IV	0.841	0.246	.041	3	view →
PDAC	DFS	Median	All	0.655	0.839	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

EGFLAM–UCEC (OS)

Open the UCEC breakdown →