EGFL7

Across TCGA cell cohorts, EGFL7 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible EGFL7-associated genes across cancer lineages are ATXN3L, IL22, and PRR27. Each is linked with EGFL7 in more than 1 cancer types. Because this analysis shows association rather than direction, both EGFL7-to-partner and partner-to-EGFL7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATXN3L grouped by EGFL7-low versus EGFL7-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EGFL7→partner) and Y-score (partner→EGFL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ATXN3L →	+0.098	+4.700	<.001	.002	3	1
OVARY	IL22 →	+0.072	+4.029	<.001	.009	3	1
OVARY	PRR27 →	+0.110	+4.029	<.001	.009	3	1
OVARY	MBD3L2B →	+0.409	+4.228	<.001	.006	3	1
OVARY	DCANP1 →	+0.006	+4.450	<.001	.004	3	1
OVARY	AFM →	+0.089	+4.700	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

ATXN3L by EGFL7 expression — OVARY

Explore this box plot interactively →