Across TCGA patient cohorts, EGFL6 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,220 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EGFL6-associated proteins across cancer lineages are P3H1, SERPINH1, and P4HA2. Each is linked with EGFL6 in more than 6 cancer types. Because this analysis shows association rather than direction, both EGFL6-to-partner and partner-to-EGFL6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EGFL6→partner) and Y-score (partner→EGFL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	P3H1 →	+0.579	+0.664	<.001	<.001	3	7
BRCA	SERPINH1 →	+0.523	+0.951	<.001	<.001	3	7
GBM	P4HA2 →	+0.674	+0.693	<.001	<.001	3	7
BRCA	CRTAP →	+0.537	+0.791	<.001	<.001	3	7
GBM	MMP14 →	+0.598	+0.657	<.001	.002	3	6
COAD	P3H3 →	+0.616	+0.877	<.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,220 associations by consensus.

Exploration

EGFL6 survival (RNA) · tumor vs normal (RNA) · all EGFL6 data types