Across TCGA patient cohorts, EGFL6 protein abundance is significantly associated with the RNA expression of many other genes, with 1,165 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EGFL6-associated genes across cancer lineages are H3-3B, EEF2K, and LEPROTL1. Each is linked with EGFL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both EGFL6-to-partner and partner-to-EGFL6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EGFL6→partner) and Y-score (partner→EGFL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	H3-3B →	+0.879	+1.625	.006	.003	3	2
LUAD	EEF2K →	-0.510	-0.476	<.001	<.001	3	1
LUAD	LEPROTL1 →	+0.372	+0.544	.001	<.001	3	1
LUAD	PIAS4 →	-0.338	-0.390	.006	.008	3	1
LUAD	VAT1 →	+0.477	+0.457	.004	<.001	3	1
LUAD	TRIM24 →	-0.658	-0.551	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,165 associations by consensus.

Exploration

EGFL6 survival (RNA) · tumor vs normal (RNA) · all EGFL6 data types