Across TCGA patient cohorts, EGFL6 mutation is significantly associated with the RNA expression of many other genes, with 3,883 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EGFL6-associated genes across cancer lineages are SNORD90, TUBGCP5, and PSMA5P1. Each is linked with EGFL6 in more than 2 cancer types. Because this analysis shows association rather than direction, both EGFL6-to-partner and partner-to-EGFL6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EGFL6→partner) and Y-score (partner→EGFL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD90 →	+0.237	+2.007	<.001	.002	3	3
UCEC	TUBGCP5 →	+0.483	+2.633	<.001	<.001	3	2
SKCM	PSMA5P1 →	+0.021	+2.806	.002	.009	3	2
GBM	RNU6-455P →	+0.456	+4.969	<.001	.009	3	2
UCEC	ONECUT1 →	+0.415	+2.281	<.001	.003	3	2
BRCA	OR5AN1 →	+0.105	+4.324	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,883 associations by consensus.

Exploration

EGFL6 survival (RNA) · tumor vs normal (RNA) · all EGFL6 data types