Across TCGA patient cohorts, EGFL6 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EGFL6-associated genes across cancer lineages are INPP4B, ATM, and PCNA. Each is linked with EGFL6 in more than 2 cancer types. Because this analysis shows association rather than direction, both EGFL6-to-partner and partner-to-EGFL6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EGFL6→partner) and Y-score (partner→EGFL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.275	-2.321	.016	.005	3	3
UCEC	ATM →	-0.373	-1.362	.019	.037	3	3
UCEC	PCNA →	+0.276	+3.700	<.001	.001	3	2
UCEC	Rad50 →	-0.193	-1.662	.024	.011	3	2
UCEC	STAT3_pY705 →	-0.393	-1.662	<.001	.011	3	2
UCEC	ASNS →	+0.380	+1.584	.002	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

EGFL6 survival (RNA) · tumor vs normal (RNA) · all EGFL6 data types