EFTUD2

Across TCGA patient cohorts, EFTUD2 protein abundance is significantly associated with the RNA expression of many other genes, with 19,452 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EFTUD2-associated genes across cancer lineages are BRIX1, CSE1L, and CCDC59. Each is linked with EFTUD2 in more than 7 cancer types. Because this analysis shows association rather than direction, both EFTUD2-to-partner and partner-to-EFTUD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFTUD2 versus BRIX1 in LSCC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFTUD2→partner) and Y-score (partner→EFTUD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BRIX1 →	+0.533	+0.149	<.001	<.001	3	8
LSCC	CSE1L →	+0.723	+0.212	<.001	<.001	3	8
HNSC	CCDC59 →	+0.552	+0.139	<.001	<.001	3	8
GBM	KIF15 →	+1.267	+0.311	<.001	<.001	3	8
BRCA	EXO1 →	+1.036	+0.193	<.001	.001	3	8
UCEC	CMSS1 →	+0.642	+0.215	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,452 associations by consensus.

EFTUD2 vs BRIX1 — LSCC

Explore this scatter interactively →