EFR3B

Across TCGA patient cohorts, EFR3B protein abundance is significantly associated with the RNA expression of many other genes, with 5,132 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EFR3B-associated genes across cancer lineages are TCIRG1, CASP1, and IQGAP1. Each is linked with EFR3B in more than 2 cancer types. Because this analysis shows association rather than direction, both EFR3B-to-partner and partner-to-EFR3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFR3B versus TCIRG1 in OV, with a Pearson correlation of -0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFR3B→partner) and Y-score (partner→EFR3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TCIRG1 →	-2.083	-1.206	<.001	<.001	3	2
OV	CASP1 →	-1.079	-0.953	.001	.002	3	2
OV	IQGAP1 →	-1.387	-1.209	.006	.005	3	2
OV	SP140L →	-1.154	-0.857	.006	.009	3	2
GBM	SPOCK3 →	+1.663	+0.316	<.001	<.001	3	2
OV	RAB6C-AS1 →	+0.347	+1.032	.003	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,132 associations by consensus.

EFR3B vs TCIRG1 — OV

Explore this scatter interactively →