EFR3B

Across TCGA patient cohorts, EFR3B mutation is significantly associated with the RNA expression of many other genes, with 3,675 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFR3B-associated genes across cancer lineages are ABHD17B, STIL, and SLF1. Each is linked with EFR3B in more than 1 cancer types. Because this analysis shows association rather than direction, both EFR3B-to-partner and partner-to-EFR3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABHD17B grouped by EFR3B-low versus EFR3B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFR3B→partner) and Y-score (partner→EFR3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ABHD17B →	+0.489	+3.348	.004	.005	3	2
COAD	STIL →	+0.560	+3.335	.005	.005	3	2
UCEC	SLF1 →	+0.581	+2.523	<.001	<.001	3	2
UCEC	ISCA1 →	+0.520	+2.938	<.001	<.001	3	2
COAD	CTDSPL2 →	+0.549	+3.348	.006	.005	3	2
COAD	GSTCD →	+0.573	+3.335	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,675 associations by consensus.

ABHD17B by EFR3B expression — COAD

Explore this box plot interactively →