EFR3B

Across TCGA cell cohorts, EFR3B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,080 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible EFR3B-associated GO terms across cancer lineages are Positive regulation of monoatomic ion transport, Transport along microtubule, and Cytoskeleton-dependent intracellular transport. Each is linked with EFR3B in more than 13 cancer types. Because this analysis shows association rather than direction, both EFR3B-to-partner and partner-to-EFR3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of monoatomic ion transport grouped by EFR3B-low versus EFR3B-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EFR3B→partner) and Y-score (partner→EFR3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of monoatomic ion transport →	-0.116	-1.462	<.001	<.001	2	14
LUNG_NSCLC_LUAD	Transport along microtubule →	+0.035	+1.006	<.001	.001	3	12
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.058	+1.250	.003	.002	3	12
SOFT_TISSUE	Positive regulation of cation transmembrane transport →	-0.129	-1.533	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	U2-type prespliceosome assembly →	+0.123	+0.387	.001	.007	3	10
LARGE_INTESTINE	Regulation of RNA export from nucleus →	+0.094	+0.545	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,080 associations by consensus.

Positive regulation of monoatomic ion transport by EFR3B expression — SOFT_TISSUE

Explore this box plot interactively →