EFR3B

Across TCGA cell cohorts, EFR3B mutation is significantly associated with the RNA expression of many other genes, with 401 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EFR3B-associated genes across cancer lineages are PPP1R2C, OPN1LW, and OPN1MW2. Each is linked with EFR3B in more than 1 cancer types. Because this analysis shows association rather than direction, both EFR3B-to-partner and partner-to-EFR3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPP1R2C grouped by EFR3B-low versus EFR3B-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFR3B→partner) and Y-score (partner→EFR3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PPP1R2C →	+0.397	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OPN1LW →	+0.039	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	OPN1MW2 →	+0.023	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	ADIG →	+0.050	+6.247	<.001	<.001	3	1
BLOOD_Lymphoma	CCT8L2 →	+0.079	+5.643	<.001	.002	3	1
SOFT_TISSUE	MORC1 →	+0.079	+3.635	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 401 associations by consensus.

PPP1R2C by EFR3B expression — BLOOD_Lymphoma

Explore this box plot interactively →