EFR3A

Across TCGA cell cohorts, EFR3A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,919 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible EFR3A-associated GO terms across cancer lineages are Negative regulation of protein-containing complex disassembly, Protein targeting to vacuole, and Cellular response to abiotic stimulus. Each is linked with EFR3A in more than 11 cancer types. Because this analysis shows association rather than direction, both EFR3A-to-partner and partner-to-EFR3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein-containing complex disassembly grouped by EFR3A-low versus EFR3A-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EFR3A→partner) and Y-score (partner→EFR3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Negative regulation of protein-containing complex disassembly →	+0.071	+0.626	<.001	<.001	3	12
BREAST	Protein targeting to vacuole →	+0.072	+1.149	<.001	<.001	3	12
LARGE_INTESTINE	Cellular response to abiotic stimulus →	+0.045	+0.887	<.001	<.001	3	12
CNS	Protein localization to vacuole →	+0.076	+0.728	<.001	<.001	3	12
LARGE_INTESTINE	Cellular response to environmental stimulus →	+0.045	+0.887	<.001	<.001	3	12
BONE	Negative regulation of protein depolymerization →	+0.108	+1.294	<.001	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,919 associations by consensus.

Negative regulation of protein-containing complex disassembly by EFR3A expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →