EFNB3

Across TCGA patient cohorts, EFNB3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,561 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible EFNB3-associated proteins across cancer lineages are EFNB3_S274, HDGFL3, and P3H3. Each is linked with EFNB3 in more than 7 cancer types. Because this analysis shows association rather than direction, both EFNB3-to-partner and partner-to-EFNB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFNB3 versus EFNB3_S274 in OV, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNB3→partner) and Y-score (partner→EFNB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EFNB3_S274 →	+0.944	+2.946	<.001	<.001	3	8
COAD	HDGFL3 →	+0.658	+0.499	<.001	<.001	3	7
LSCC	P3H3 →	+0.602	+0.721	<.001	<.001	3	7
CCRCC	PCOLCE →	+0.829	+0.340	<.001	<.001	3	7
UCEC	TGFB1I1 →	+0.752	+0.885	.002	.005	3	6
UCEC	TIMP2 →	+0.597	+1.301	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,561 associations by consensus.

EFNB3 vs EFNB3_S274 — OV

Explore this scatter interactively →