EFNB3

Across TCGA patient cohorts, EFNB3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,455 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EFNB3-associated genes across cancer lineages are FSD1, ACRV1, and KLHL35. Each is linked with EFNB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFNB3-to-partner and partner-to-EFNB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFNB3 versus FSD1 in GBM, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNB3→partner) and Y-score (partner→EFNB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FSD1 →	+0.929	+0.571	<.001	<.001	3	2
UCEC	ACRV1 →	+1.002	+0.729	.004	<.001	3	2
UCEC	KLHL35 →	+0.868	+0.713	<.001	<.001	3	2
GBM	CASKIN1 →	+0.936	+0.513	<.001	<.001	3	2
UCEC	CENPK →	+0.818	+0.691	.005	<.001	3	1
UCEC	HJURP →	+1.227	+0.702	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,455 associations by consensus.

EFNB3 vs FSD1 — GBM

Explore this scatter interactively →