EFNB3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, EFNB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,094 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EFNB3-associated GO terms across cancer lineages are Locomotory exploration behavior, Negative regulation of myoblast fusion, and Positive regulation of stem cell population maintenance. Each is linked with EFNB3 in more than 14 cancer types. Because this analysis shows association rather than direction, both EFNB3-to-partner and partner-to-EFNB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Locomotory exploration behavior grouped by EFNB3-low versus EFNB3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNB3→partner) and Y-score (partner→EFNB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONELocomotory exploration behavior →+0.260+2.520<.001<.001315
OESOPHAGUSNegative regulation of myoblast fusion →+0.169+2.763<.001<.001314
LUNG_SCLCPositive regulation of stem cell population maintenance →+0.096+2.415.003<.001314
STOMACHRegulation of stem cell population maintenance →+0.107+1.678<.001.001314
STOMACHRegulation of DNA-templated transcription elongation →+0.084+2.324<.001<.001314
OESOPHAGUSTranscription initiation at RNA polymerase II promoter →+0.082+1.918<.001<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,094 associations by consensus.

Locomotory exploration behavior by EFNB3 expression — BONE

Box plot of Locomotory exploration behavior in EFNB3-low vs EFNB3-high samples in BONE.

Explore this box plot interactively →

Exploration